Slow tumor growth in pancreatic cancer by cutting off cell communication

Study how the different cells that make up a pancreatic cancer tumor communicate to promote growth and design a way to cut off this communication.

Cell Therapy Translational Research Laboratory at University of Toronto
Cell Therapy Translational Research Laboratory at University of Toronto
Toronto, Canada
Dr. Armand Keating

Dr. Armand Keating







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Project Summary

Roughly 90% of cells that make up pancreatic cancer tumors are actually not cancerous. We want to investigate the role of these special cells, called stromal cells, in creating an environment for the tumor to grow so we can disrupt it.

We’ve been studying similar cells derived from bone marrow in our lab for years and want to apply our learnings to pancreatic cancer cells.

At the end of the start-up phase, we anticipate validating our observations and generating a list of potential pancreatic cancer factors that stimulate stromal cells to promote cancer growth that we can investigate further.

Project Length9-12 months
GoalTo validate our observations and generate a list of factors that stimulate growth that we can investigate further.
Research TypeExploratory
Research Team