University of Washington, Matt Kaeberlein, PhD
Biological aging is the single greatest causal factor for most major sources of disease and disability, but these mechanisms remain poorly understood.
Research Institute
Researchers
Matt Kaeberlein, PhD
Daniel Promislow, DPhil
Kate Creevy, DVM, MS, DACVIM
The Dog Aging Project is the largest longevity study in the world. It is an open-access, community science project that has recruited more than 50,000 people and their dogs to collect data aimed at understanding and modifying biological aging in order to increase healthy longevity in dogs and ultimately people. To date, the project has published more than 50 peer-reviewed papers, created an open-access database with more than 36 million data points, built a veterinary biobank with more than 10,000 samples, and initiated the first ever longevity clinical trial to determine whether rapamycin can increase healthspan and lifespan in dogs.
Project Length | 2 years |
Goal | Our goal is to (1) support the veterinary and computational infrastructure of Dog Aging Project for up to two years in order to facilitate long-term support from NIH and (2) complete the TRIAD veterinary clinical trial to determine whether or not rapamycin increases lifespan and healthspan in companion dogs. |
Research Type | Biomedical and veterinary research |