Hacking the dark genome to find a cure for breast cancer
Scientists match a breakthrough gene hacking therapy with an aggressive form of breast cancer that disproportionately affects young women.
Research Institute
Researchers
Dr. Mathieu Lupien, PhD
Dr. David Cescon, MD, PhD
Project Summary
Triple-Negative Breast Cancer (TNBC) is an aggressive form of breast cancer more common in young women. The problem is that current treatment fails for over 40% of TNBC patients. New and better treatments are needed to cure women with TNBC.
The goal of this study is to stop aggressive breast cancer in its tracks by targeting and hacking the switches of cancer-causing genes. We have already used this approach to block relapse following chemotherapy in a small cohort of TNBC model systems. We now need to translate this success into practical application.
| Project Length | 9-12 months |
| Goal | To surface a potential cure for women with highly aggressive forms of breast cancer |
| Research Type | Pre-Clinical |
| Research Team |