Develop a deep understanding of ME/CFS through genomic sequencing

Study to develop an intense genetic comprehension of ME/CFS to inform diagnoses, treatments, and prevention measures for this long misunderstood and understudied condition

Albert Einstein College of Medicine
Albert Einstein College of Medicine
New York, United States
John Greally, DMed PhDSrilakshmi Raj, PhD

John Greally, DMed PhD

Srilakshmi Raj, PhD

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Project Summary

Patients with ME/CFS have an inability to recover after exercise and other forms of stress. It’s a condition that builds over time and can lower energy levels to extreme lows. With symptoms of overwhelming fatigue, pain, dizziness, and more, ME/CFS is difficult to diagnose, treat, and understand. Our plan is to use samples from patients enrolled in the NIH-funded Center for Solutions for ME/CFS, to perform genomic sequencing on hundreds of genomes in a pilot phase. We will then analyze the genomic sequence to find the genes likely to contribute to ME/CFS patients. Finally, we will publish the findings to lead the conversation on ME/CFS genetics and attract larger-scale federal funding.

Project Length6 months
GoalTo perform the first large scale genomic study of hundreds of people with confirmed ME/CFS, with the goal of identifying new ways of diagnosing the condition and ultimately a cure for the condition
Research TypeExploratory research
Research Team